Acetaminophen toxicity demands emergency medical treatment; left untreated, significant morbidity or death can result. Although different dosing strategies for N-acetylcysteine (NAC) have been proposed, no singular dosing strategy has been identified as superior. While recent guidelines have been released, there are many unanswered questions regarding preferred NAC dosing regimens and the use of adjunctive treatment agents. Through the use of patient cases, this interactive session will discuss real-world supratherapeutic acetaminophen ingestions, management of the pediatric patient with acetaminophen toxicity, and implementation of adjunctive agents outside of NAC. In addition, patient safety and monitoring of these dosing regimens will be reviewed. Evidence-based recommendations on the use of extracorporeal treatments for acetaminophen toxicity will also be reviewed.
This activity is approved for Board Certified Pediatric Pharmacy Specialist (BCPPS), Board Certified Crtical Care Pharmacist (BCCCP), and Board Certified Emergency Medicine Pharmacist (BCEMP) recertification credit.
The BCCCP, BCPPS, BCEMP Clinical Sessions are part of the professional development program for the recertification of board-certified Critical Care, Pediatric, or Emergency Medicine pharmacists by the Board of Pharmacy Specialties and jointly provided by ACCP and the American Society of Health-System Pharmacists (ASHP). In order to earn the BCCCP, BCPPS, BCEMP recertification credit, participants must attend the session, claim the continuing pharmacy education credit, and pass the associated posttest. Access to the Clinical Sessions posttests will be available on December 18, 2024, at www.accp.com/myaccount to anyone who has purchased access to the BCCCP, BCPPS, or BCEMP posttests. For participants who have not purchased access to the posttests, access can be purchased until 5:30 p.m. on Tuesday, October 15, at the ACCP Registration Desk. The deadline to submit posttests for these sessions will be December 16, 2025.
Learning Objectives
1. Evaluate current guideline recommendations for patients presenting with acetaminophen toxicity.
2. Develop an effective treatment regimen for the management of a patient presenting with acetaminophen toxicity.
3. Develop monitoring strategies for the different medications used to treat acetaminophen toxicity.
4. Design an effective treatment plan for patients requiring adjunctive treatment options for acetaminophen toxicity.
1. Evaluate current guideline recommendations for patients presenting with acetaminophen toxicity.
2. Develop an effective treatment regimen for the management of a patient presenting with acetaminophen toxicity.
3. Develop monitoring strategies for the different medications utilized to treat acetaminophen toxicity.
4. Design an effective treatment plan for patients requiring adjunctive treatment options for acetaminophen toxicity.